[username@host]:<~$>alias | grep screen
alias chat.screen='screen -x -U -R chat -p "quakenet" -O -c ~/.bigscreenrc'

^stick that in your bash rc or profile..

[username@host]:<~$>cat .bigscreenrc 
screen -t centerim centerim
screen -t quakenet ./.irc/bin/quakenet.epic.lice
screen -t blabber ./.irc/bin/blabber.epic.lice 
screen -t openprojects ./.irc/bin/openprojects.epic.lice
screen -t efnet ./.irc/bin/efnet.epic.lice
screen -t ircnet ./.irc/bin/ircnet.epic.lice
screen -t mutt /usr/local/bin/mutt
screen -t mutt-username /usr/local/bin/mutt -F .muttrc-username 

select 1

autodetach        on
defmonitor        on
defsilence        off
crlf              off
deflogin          off
vbell             on
msgwait           10
startup_message   off
msgminwait        2 
silencewait      15
vbell_msg       " RIBBIT! RIBBIT! "

and it's that simple, wietze!